Biologist

Position Title: Biologist

Work Location: Worcester, MA 01604

Assignment Duration: 12 months (possibility of extension)

Position Summary:

Discovery Biotherapeutics is seeking a research scientist to join a dynamic team supporting biologics drug discovery and multispecifics engineering. This position will impact projects by expressing, purifying, and characterizing multispecific biologics.

Key Responsibilities:

* Responsible for expression, purification, and remediation of multispecific biologics.

* Characterize multispecific biologics (SEC, LC/MS, DSF, SDS-PAGE, endotoxin).

* Utilize automation (e.g. Hamilton, AssayMap, Kingfisher) in biologics discovery processes.

* Coordinate sample handoffs and aliquoting as necessary to enable timely delivery of material to cross-functional teams.

Qualifications & Experience:

* Position will be hired based on level of experience.

* BS or MS in biology or related field with 2+ years (BS), or 0+ years (MS) of pharmaceutical and/or relevant experience.

* Experience with protein and biologics expression, purification, and characterization.

* Knowledge of analytical techniques to characterize proteins (e.g. SEC, MS, DSF).

* Excellent organizational skills to track multiple requests and sample deliveries to ensure timely material delivery.

* Familiarity with report generation and electronic notebook systems.

* Skilled in usage of software programs, including MS Excel, Powerpoint, Word.

* Excellent communication skills to convey results of experiments and plan next steps.

Preferred:

* Experience with multispecific biologics.

* Hands-on with analytical techniques including SEC, MS, endotoxin measurement, and DSF.

* Hands-on experience with SEC, HIC, and IEX purification of complex biologics utilizing AKTA platforms.

* Experience with automation (e.g. Tecan, Hamilton, etc).

* Experience with antibody engineering, design, and optimization.