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Senior Principal Analyst, Platform Operations

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Sep 05, 2025

Job Description

General Summary:

The Business Engagement & Technology Senior Principal Analyst will be a key technical resource in ensuring the planning and delivery of key commercial-off-the-shelf (COTS) and a wide range of custom solutions in support of their business partners. The Business Engagement & Technology Senior Principal Analyst will partner with business leadership to develop capabilities and systems roadmaps that align to support business strategy. Additionally, the Business Engagement & Technology Senior Principal Analyst will ensure team members maintain reliable, scalable and compliant systems that easily meet business needs by efficient delivery and enhancements that provides opportunities for developing and implementing innovative solutions and integrations. This person will also successfully manage the day-to-day responsibilities of a team and ensure their success and career development.

Key Duties and Responsibilities:

  • Become a trusted partner of the business leaders within their remit
  • Understand their needs and vision, and deliver technology solutions to support and enable their goals and objectives
  • Engage as a key participant in the strategic business planning process for their business partners
  • Provide insights on how technology can improve business processes to enable operating efficiencies and support the achievement of business goals and objectives.
  • Articulate and maintain a technology strategy to support and advance the business' objective. This strategy should factor in an understanding of future directions of the business area, as well as changes in the technology landscape.
  • Execute the technology strategy by leading the evaluation, selection, implementation, and ongoing maintenance of technology solutions.
  • Develop and maintain a long term life cycle plan for the ongoing maintenance and management of systems.
  • Manage relationships with our strategic software vendors and service providers
  • Establish, track and report on project value drivers and financial impact
  • Build and develop a team of Vertex employees, as well as potentially overseeing managed services providers
  • Work closely with DTE Compliance, Internal Audit, and Quality Assurance groups as needed to ensure compliance with all appropriate regulations, as well as our DTE system lifecycle and change management requirements

Knowledge and Skills:

  • In-depth and specialized knowledge in the core disciplines of project management, business analysis, solution design, delivery and training
  • Significant experience in building productive partnerships with business stakeholders and influencing them to take action
  • In-depth and specialized understanding of the business, processes, and any appropriate regulatory environments
  • Results oriented manager with a proven track record of on-time project delivery for large, complex projects with global stakeholders
  • Exceptional written and verbal communication skills and ability to present in a clear and concise manner to all audiences
  • Exceptional analytical, quantitative, problem-solving, and prioritization skills, including the development of business cases/ value propositions
  • Substantial program/ project management, demand management, resource management and system life cycle expertise
  • Strong analytical and problem-solving abilities including development of business case / value propositions
  • Proven capabilities in people management and building high-performing teams
  • Prior experience with running IT managed services or outsourced/ offshore teams
  • Superior MS Office skills, including MS Project & Visio, Excel and PowerPoint Experience
  • Strong experience in Agile methodology

Education and Experience:

  • Bachelor's degree in technology discipline or equivalent
  • Typically requires 9 years relevant business systems in the Life Sciences industry, or the equivalent combination of education and experience

Pay Range:

$158,800 - $238,100

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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