Associate Scientist II, CNS

The Research Department at Alnylam is seeking a motivated Associate Scientist II to join our team to support the biology group in research including CNS and emerging tissues. We are seeking a highly organized individual that can work quickly and efficiently in a fast-paced laboratory setting. This ideal candidate will be a strong team player, capable of coordinating tasks with various stakeholders to meet deadlines.

This position is onsite and will be primarily located in Cambridge, MA.

Key Responsibilities

• Contribute to the design and execution of studies to characterize molecules for RNAi therapeutic programs, including rodent disease models.
• Develop and conduct assays such as qPCR, western blot, ELISA, that support in vivo studies.
• Conduct in vivo procedures in both rats and mice, including therapeutic administration using established methodologies.
• Analyze, report, and present scientific data in group meetings.
• Prepare clearly articulated experimental reports and data presentations.
• Prepare of SOPs/protocols.
• Track samples in databases including but not limited to Electronic Laboratory Notebook (ELN), Laboratory Information Management System (LIMS), Smart Refrigeration systems, Smartsheet's and other proprietary databases.
• Adapt quickly to changing priorities in a dynamic work environment.
• Communicate openly and directly with lab groups to provide sufficient solutions that will work for all team members.

Qualifications

• Minimum B.S. degree in a life sciences-related discipline such as Molecular Biology, Cell Biology, or Genetics
• Basic rodent in vivo skills (animal handling, subcutaneous/intravenous dosing, blood collection, and necropsy/tissue dissection expertise). The ability to collect peripheral tissues, dorsal root ganglia (DGRs), and brain regions is highly desirable.
• Demonstrate keen knowledge of experimental design, underlying scientific principles, and the ability to rigorously and independently analyze results, propose future directions, and generate clear reports
• Must be flexible, open to new tasks and challenges and able to work on tight deadlines.
• Exceptional interpersonal skills and the ability to function at a high capacity within a fast-paced team environment.
• Excellent attention to detail, organizational skills, eagerness to learn, and the ability to follow written and verbal instruction.
• Working knowledge of standard Microsoft Office applications including Excel, GraphPAD, Outlook, PowerPoint, and Word.
• Familiarity with laboratory automation and liquid handling systems is a plus.
  
  

About Alnylam:Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our culture:Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as the #1 Large Employer by Boston Globe Top Places to Work in 2023 for the third consecutive year, one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients. Qualified applicants will receive consideration for employment without regard to their race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, ethnicity, marital status, protected veteran status, disability, or any other characteristics prohibited by law.